Updated November 2026
Top 100 biotech VC firms
Funds matching
406
Top 100 ranked below
Median est. dry powder
$120.3M
Across the 100 ranked funds
Top regions
- Asia47
- North America38
- Europe11
Top stages
- Early Stage95
- Series B93
- Series A90
Ranked by estimated dry powder
Largest first. Click a fund for its full profile.
- 1USNorth AmericaAngelGrantSeed+11$696K–$57.5M$10.8B
- 2USNorth AmericaAngelGrantSeed+12$100K–$17.7M$2.9B
- 3ChinaAsiaSeries ASeries BSeries C+1$14.3M–$71.5M$994.7M
- 4FranceEuropeAngelSeedSeries A+7$1.1M–$18.8M$876.4M
- 5ChinaAsiaAngelSeedSeries A+5$309.7K–$1.5M$849.4M
- 6ChinaAsiaSeries ASeries BSeries C+3$344.5K–$10.7M$840M
- 7USNorth AmericaSeries ASeries BSeries C+4$100K–$57.8M$814.5M
- 8UKEuropeSeedSeries ASeries B+4$4.3M–$44.8M$646M
- 9USNorth AmericaAngelSeedSeries A+10$2.6M–$20.6M$636.5M
- 10USNorth AmericaSeedSeries ASeries B+5$1.6M–$30M$585.1M
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About this list
Every firm here mentions biotech in its profile and invests at venture stages. Biotech rounds are large and slow, so firms with more capital left to deploy are better placed to lead and follow on. Check each firm's past investments for your modality before you pitch.
Funds are ranked by estimated dry powder, largest first, with the name breaking ties. Dry powder is a firm-level estimate of capital raised but not yet invested, from licensed private-markets data, so treat it as a guide rather than a quote. Firms that also run buyout strategies are left out, because most of their dry powder is buyout capital. Cheque sizes are estimated from fund sizes.
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Questions about this list
Who are the top biotech VC firms?
Ranked by estimated dry powder, the top five are Founders Fund, Y Combinator, State Ventures Innovation Investment, Sofinnova Partners and Zhongguancun Science City Capital. The full ranking of 100 firms is above.
Which firm has the most capital to deploy on this list?
Founders Fund, with an estimated $10.8B of dry powder.
What is this list based on?
Every firm here mentions biotech in its profile and invests at venture stages. Biotech rounds are large and slow, so firms with more capital left to deploy are better placed to lead and follow on. Check each firm's past investments for your modality before you pitch.
How is dry powder estimated?
From the size and vintage of each manager's recent funds and how much of them is likely already invested. It is an estimate, best used to compare firms rather than as an exact figure.
Get the partner to contact at each fund.
The Pro and Team plans add partner emails and LinkedIn, exports and outreach drafts for every fund on these lists.