The Column Group
Est. dry powder
$585.1M
Raised, not yet invested
AUM
$4B
Assets under management
Latest fund
$259M
The Column Group
Est. cheque size
$1.6M–
From fund sizes
Deals, last 12 months
5
Last seen investing Oct 2026
About The Column Group
The Column Group (TCG) is a US-based private equity firm involved in venture capital investments. The firm invests in early stage, late stage, and other investments that focus on healthcare, biotechnology, and other industries across North America, and the US.
- Type
- Venture Capital Firm
- Headquarters
- San Francisco, California, US
- Stages
- SeedSeries ASeries BSeries CSeries DSeries ESeries FEarly Stage
- Est. cheque size
- $1.6M–$30M
- Sectors
- Healthcare
- Regions
- North America
- Strategies
- Pre-Seed, Seed, Series A
Where they invest
From deals and portfolio companies on record
Most frequent rounds
- Series A48
- Series B39
- Series C20
- Series D12
- Series E5
Across 137 deals
Portfolio sectors
- Biotechnology35
- Pharmaceuticals9
- Healthcare1
Across 45 companies
Portfolio countries
- US45
Across 45 companies
Recent investments
Newest 5 of 137
- Unspecified Round$94M
TriGemX Bio, Inc.
Oct 2026 · Unspecified Round
- Series B$77M
InduPro, Inc.
Aug 2026 · Series B
- Series B$73.8M
Nura Bio Inc.
Jun 2026 · Series B
- Series A—
Tortugas Neuroscience, Inc.
Apr 2026 · Series A
- Series B$120M
Atavistik Bio, Inc.
Dec 2025 · Series B
Offices
2 locations
- San Francisco, California, USHQ
- South San Francisco, California, US
Questions about The Column Group
How much does The Column Group invest per deal?
Based on the size of its funds, The Column Group writes estimated cheques of $1.6M–$30M. Lead cheques usually sit at the top of that range and follow-on cheques lower.
What stages does The Column Group invest in?
The Column Group has invested at Seed, Series A, Series B, Series C, Series D and Series E. Its most frequent rounds on record are Series A, Series B and Series C.
How much capital does The Column Group have left to invest?
The Column Group has an estimated $585.1M in dry powder: capital it has raised but not yet invested.