Prolific Machines

BiotechnologySeries BEmeryville, USprolific-machines.com

Latest round

Series B

Last raised

Oct 2026

Total raised

$105M

Investors

18

About Prolific Machines

Based in California, US, Prolific Machines, Inc. is a developer of a cell manufacturing platform to enable stem cells to be maintained and differentiated, without any recombinant proteins in the feedstock.'s core technology utilises a photomolecular platform. The platform’s light-sensitive proteins (LSPs) directly manipulate various cellular processes. These LSPs, naturally occurring in organisms, are engineered and introduced into target cells. Prolific’s platform enhances the production of complex therapeutic proteins, addressing issues like folding, aggregation, and cytotoxicity while enabling post-translational modifications. The technology facilitates the production of valuable food proteins, including those used in supplements and infant formulas. Additionally, Prolific’s control cell differentiation improves yield and structure in cultured meat production. The platform allows for the design and spatial patterning of reproducible disease models, enhancing research and drug development, creating complex tissue structures, and supporting advancements in regenerative medicine.

Who invested in Prolific Machines

18 investors across 5 rounds

See all investors in Prolific Machines

Sign up free to see every VC on the cap table, the rounds they joined, and how much each round raised.

Funding rounds

  1. Series B

    Oct 16, 2026

    Amount

    $50M

    Investors

    Locked

  2. Series B

    Jun 6, 2024

    Amount

    $55M

    Investors

    Locked

  3. Series A

    Nov 19, 2021

    Amount

    Undisclosed

    Investors

    Locked

  4. Seed

    Mar 22, 2021

    Amount

    Undisclosed

    Investors

    Locked

  5. Seed

    May 25, 2020

    Amount

    Undisclosed

    Investors

    Locked

Questions about Prolific Machines

Who invested in Prolific Machines?

Prolific Machines has 18 investors on record across 5 venture rounds. Sign up free to see every VC on the cap table and the rounds they joined.

How much funding has Prolific Machines raised?

Prolific Machines has raised 5 venture rounds. Sign up free to see how much each round raised and the total.

When did Prolific Machines last raise money?

Prolific Machines's most recent round on record is a Series B, in Oct 2026.

What does Prolific Machines do?

Based in California, US, Prolific Machines, Inc.

Where is Prolific Machines headquartered?

Prolific Machines is headquartered in Emeryville, US.

Which VCs invest in companies like Prolific Machines?

Among active investors with capital left to deploy, Andreessen Horowitz, Founders Fund, Accel and Thrive Capital back biotechnology companies at Prolific Machines's stage. Their profiles are linked below.

Raising like Prolific Machines? Find the right VCs.

Capital Atlas matches your startup to active investors by stage, sector and region.

Free to start. Upgrade when you're ready to reach out.