Crystalys Therapeutics

BiotechnologySeries BSan Diego, UScrystalystx.com

Latest round

Series B

Last raised

Jul 2026

Total raised

$335M

Investors

21

About Crystalys Therapeutics

Crystalys Therapeutics Inc. is a US-based biotechnology company dedicated to developing innovative therapeutics aimed at treating gout and improving patient outcomes. Founded in 2025 and headquartered in San Diego, California, Crystalys Therapeutics Inc. focuses on developing treatments for gout. Founded in 2025 and headquartered in San Diego, California, Crystalys Therapeutics Inc. focuses on developing treatments for gout. Crystalys Therapeutics Inc. was co-founded by James Mackay (CEO), Nihar Bhakta, Ashwin Ram, DeAnne Reid, and BT Slingsby. In July 2026, Crystalys Therapeutics Inc. Crystalys Therapeutics’ lead investigational product is dotinurad, a once-daily oral, highly selective URAT1 inhibitor being developed as a potential second-line treatment for gout. Dotinurad is being evaluated in the Phase 3 RUBY and TOPAZ trials and the Phase 2 AMETHYST trial. Crystalys generates revenue primarily through B2B partnerships, direct sales to healthcare institutions, and potential licensing agreements with pharmaceutical partners, employing transaction structures involving upfront payments and royalties, although specific pricing has not been disclosed.

Who invested in Crystalys Therapeutics

21 investors across 2 rounds

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Funding rounds

  1. Series B

    Jul 22, 2026

    Amount

    $130M

    Investors

    Locked

  2. Series A

    Sep 30, 2025

    Amount

    $205M

    Investors

    Locked

Questions about Crystalys Therapeutics

Who invested in Crystalys Therapeutics?

Crystalys Therapeutics has 21 investors on record across 2 venture rounds. Sign up free to see every VC on the cap table and the rounds they joined.

How much funding has Crystalys Therapeutics raised?

Crystalys Therapeutics has raised 2 venture rounds. Sign up free to see how much each round raised and the total.

When did Crystalys Therapeutics last raise money?

Crystalys Therapeutics's most recent round on record is a Series B, in Jul 2026.

What does Crystalys Therapeutics do?

Crystalys Therapeutics is a biotechnology company.

Where is Crystalys Therapeutics headquartered?

Crystalys Therapeutics is headquartered in San Diego, US.

Which VCs invest in companies like Crystalys Therapeutics?

Among active investors with capital left to deploy, Andreessen Horowitz, Founders Fund, Accel and Thrive Capital back biotechnology companies at Crystalys Therapeutics's stage. Their profiles are linked below.

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