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Funds/North America/Flagship Pioneering

Flagship Pioneering

Venture Capital FirmCambridge, US·Founded 2000·flagshippioneering.com

Est. dry powder

$3.1B

Raised, not yet invested

AUM

$14B

Assets under management

Latest fund

—

Life Science Fund No. 2, size not reported

Est. cheque size

$2.4M–$38.6M

From fund sizes

Deals, last 12 months

2

Last seen investing Apr 2026

About Flagship Pioneering

Flagship Pioneering based in the US, is a private equity firm and established in 2000. Firm that consists primarily of seed and early-stage investments, with some later stage value investments, invests in three principal business sectors: therapeutics; medical technologies; and sustainability/clean technology. The firm generally assembles a syndicate with other leading venture firms as the company matures. Flagship Pioneering, originally called as NewCoGen or New Company Generation and formerly known as Flagship Ventures, operates through two synergistic units: Venture Labs which invents and launches transformative companies, and Venture Capital, which finances and realizes innovative early-stage companies across the US.

Type
Venture Capital Firm
Headquarters
Cambridge, Massachusetts, US
Stages
SeedSeries ASeries BSeries CSeries DSeries ESeries FSeries G+2
Est. cheque size
$2.4M–$38.6M
Sectors
Healthcare, Information Technology, Diversified
Regions
North America

Where they invest

From deals and portfolio companies on record

Most frequent rounds

  • Series B89
  • Series A88
  • Series C61
  • Series D25
  • Series E16

Across 368 deals

Portfolio sectors

  • Biotechnology48
  • Pharmaceuticals13
  • Software7
  • Medical Devices & Equipment5
  • Food4

Across 149 companies

Portfolio countries

  • US96
  • Bangladesh1
  • Denmark1
  • Switzerland1
  • UK1

Across 149 companies

Recent investments

Newest 5 of 368

DateCompanyRoundAmountCo-investors
  1. Apr 2026

    Serif Bio­med­i­cines, Inc.

    Apr 2026 · Unspecified Round

    Unspecified Round$50M—
  2. Apr 2026

    Harbinger Health, Inc.

    Apr 2026 · Unspecified Round

    Unspecified Round$100M—
  3. Oct 2025

    Expedition Medicines, Inc.

    Oct 2025 · Series B

    Series B$50M—
  4. Oct 2025

    Lila Sciences

    Oct 2025 · Series A

    Series A$115MHong Shan, General Catalyst Partners, Lux Capital, Andreessen Horowitz +7
  5. Sep 2025

    Extuitive, Inc.

    Sep 2025 · Series A

    Series A$15.6M—

Offices

2 locations

  • Cambridge, Massachusetts, USHQ
  • Cambridge, Massachusetts, US

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Ranks on

  • #11Top 100 seed VC funds in North America
  • #11Top 100 healthcare VC funds
  • #12Top 100 VC firms in the US
  • #12Top 100 Series A VC funds in North America

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Questions about Flagship Pioneering

How much does Flagship Pioneering invest per deal?

Based on the size of its funds, Flagship Pioneering writes estimated cheques of $2.4M–$38.6M. Lead cheques usually sit at the top of that range and follow-on cheques lower.

What stages does Flagship Pioneering invest in?

Flagship Pioneering has invested at Seed, Series A, Series B, Series C, Series D and Series E. Its most frequent rounds on record are Series B, Series A and Series C.

How much capital does Flagship Pioneering have left to invest?

Flagship Pioneering has an estimated $3.1B in dry powder: capital it has raised but not yet invested.

What has Flagship Pioneering invested in recently?

Recent investments include Serif Bio­med­i­cines, Inc., Harbinger Health, Inc. and Expedition Medicines, Inc.. It made 2 investments in the last 12 months.

Where is Flagship Pioneering based?

Flagship Pioneering is headquartered in Cambridge, US. It has 1 other office.

How do I contact Flagship Pioneering?

Partner names, emails and LinkedIn profiles for Flagship Pioneering are on the Capital Atlas Pro and Team plans, which also draft outreach and track replies. Check the stages and cheque size above first, so you pitch a firm that fits your round.

Similar investors in North America

Andreessen HorowitzUS · Cheque $3.8M–$81.3M$21.5B dry powderFounders FundUS · Cheque $696K–$57.5M$10.8B dry powderAccelUS · Cheque $1.1M–$31.9M$9.4B dry powderThrive CapitalUS · Cheque $225K–$30.6M$8.9B dry powderKleiner PerkinsUS · Cheque $2M–$32.5M$4.5B dry powderLightspeed Venture PartnersUS · Cheque $1.7M–$35.8M$4B dry powder

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