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Funds/North America/ARCH Venture Partners

ARCH Venture Partners

Venture Capital Firm (Investor)Chicago, US·Founded 1986·archventure.com

Est. dry powder

$3.4B

Raised, not yet invested

AUM

$2B

Assets under management

Latest fund

—

Healthcare Focus Fund, size not reported

Est. cheque size

$2.2M–$87.6M

From fund sizes

Deals, last 12 months

28

Last seen investing Sep 2026

About ARCH Venture Partners

ARCH Venture Partners is a US-based venture capital firm that makes early-stage, start-up, and seed investments in advanced technology companies. The firm's industry focus includes semiconductors, clean technology, electronic components, network infrastructure, IT security, wireless, pharmaceuticals, medical devices, diagnostic and drug discovery platforms, nanotechnology, and microtechnology sectors across US.

Type
Venture Capital Firm (Investor)
Headquarters
Chicago, Illinois, US
Stages
GrantSeedSeries ASeries BSeries CSeries DSeries ESeries F+4
Est. cheque size
$2.2M–$87.6M
Sectors
Healthcare, Information Technology, Diversified
Regions
North America
Strategies
Pre-Seed, Seed, Series A

Where they invest

From deals and portfolio companies on record

Most frequent rounds

  • Series A198
  • Series B172
  • Series C80
  • Series D38
  • Seed20

Across 601 deals

Portfolio sectors

  • Biotechnology74
  • Medical Devices & Equipment7
  • Software6
  • Healthcare Specialists4
  • Pharmaceuticals4

Across 271 companies

Portfolio countries

  • US89
  • UK5
  • China3
  • Ireland1
  • Sweden1

Across 271 companies

Recent investments

Newest 5 of 601

DateCompanyRoundAmountCo-investors
  1. Sep 2026

    Ramona

    Sep 2026 · Series A

    Series A$25M+ND Capital, Fall Line Capital, Murchison Capital Partners, Overlap Holdings +2
  2. Sep 2026

    Encoded Therapeutics, Inc.

    Sep 2026 · Series F

    Series F$275MVenrock, GV, Janus Henderson Investors, Invus Financial Advisors +7
  3. Sep 2026

    Moonwalk Biosciences, Inc.

    Sep 2026 · Series B

    Series B$70MKhosla Ventures, Alpha Wave Global, Eli Lilly & Company, Gaorong Ventures +2
  4. Aug 2026

    Happy Health, Inc.

    Aug 2026 · Series B

    Series B$32.7MOpenLoop
  5. Jul 2026

    LifeMine Therapeutics, Inc.

    Jul 2026 · Series E

    Series E$150.5MGates Foundation Trust, GlaxoSmithKline, GV, RA Capital Management +4

Offices

4 locations

  • Chicago, Illinois, USHQ
  • San Francisco, California, US
  • Austin, Texas, US
  • Mercer Island, Washington, US

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Ranks on

  • #9Top 100 healthcare VC funds
  • #10Top 100 seed VC funds in North America
  • #11Top 100 VC firms in the US

Questions about ARCH Venture Partners

How much does ARCH Venture Partners invest per deal?

Based on the size of its funds, ARCH Venture Partners writes estimated cheques of $2.2M–$87.6M. Lead cheques usually sit at the top of that range and follow-on cheques lower.

What stages does ARCH Venture Partners invest in?

ARCH Venture Partners has invested at Grant, Seed, Series A, Series B, Series C and Series D. Its most frequent rounds on record are Series A, Series B and Series C.

How much capital does ARCH Venture Partners have left to invest?

ARCH Venture Partners has an estimated $3.4B in dry powder: capital it has raised but not yet invested.

Similar investors in North America

Andreessen HorowitzUS · Cheque $3.8M–$81.3M$21.5B dry powderFounders FundUS · Cheque $696K–$57.5M$10.8B dry powderAccelUS · Cheque $1.1M–$31.9M

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  • #11Top 100 Series A VC funds in North America
  • Work at ARCH Venture Partners?

    Claim this profile to correct your thesis and cheque size, and choose how founders reach you.

    Claim this profile
    What has ARCH Venture Partners invested in recently?

    Recent investments include Ramona, Encoded Therapeutics, Inc. and Moonwalk Biosciences, Inc.. It made 28 investments in the last 12 months.

    Where is ARCH Venture Partners based?

    ARCH Venture Partners is headquartered in Chicago, US. It has 3 other offices.

    How do I contact ARCH Venture Partners?

    Partner names, emails and LinkedIn profiles for ARCH Venture Partners are on the Capital Atlas Pro and Team plans, which also draft outreach and track replies. Check the stages and cheque size above first, so you pitch a firm that fits your round.

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