# Spyre Theraputics

Startup profile on Capital Atlas: https://capitalatlas.ai/startups/spyre-theraputics

- Industry: Biotechnology
- Headquarters: Austin, US
- Website: https://spyre.com/
- Total disclosed funding: $56M
- Latest round: Series B (Mar 10, 2015)
- Investors on record: 12

## About

Founded in 2013 and based in Texas, US, Spyre Theraputics, Inc. operates as a biotechnology technology company that develops and provides human enzyme therapeutics to treat patients suffering from rare genetic diseases and cancer. The firm as of July 2024, is led by its CFO, Scott Burrows and VP Corporate Controller, Jonathan Campbell.

Spyre Therapeutics is dedicated to advancing the treatment landscape for Inflammatory Bowel Disease (IBD) through its therapeutic approaches like antibodies and rational therapeutic combinations. The company improves outcomes for patients with conditions like ulcerative colitis (UC) and Crohn’s disease (CD). Spyre's portfolio includes novel monoclonal antibody candidates like SPY001 and SPY002, designed with extended half-lives and targeting specific mechanisms of IBD pathology.

## Funding rounds

- Series B, Mar 10, 2015, $44M — OrbiMed Advisors, Novartis Venture Fund, Lilly Ventures, Venrock, Jennison Associates, RA Capital Management, Rock Springs Capital, UT Horizon Fund, Ally Bridge Group, New Ground Ventures, Cowen Investment Management
- Series A, Feb 3, 2014, $12M — Novartis Venture Fund, Lilly Ventures, KBI Biopharma

## Investors

- Novartis Venture Fund (https://capitalatlas.ai/funds/novartis-venture-fund) — Series A, Series B
- Lilly Ventures (https://capitalatlas.ai/funds/lilly-ventures) — Series A, Series B
- KBI Biopharma — Series A
- OrbiMed Advisors (https://capitalatlas.ai/funds/orbimed-advisors) — Series B
- Venrock (https://capitalatlas.ai/funds/venrock) — Series B
- Jennison Associates — Series B
- RA Capital Management (https://capitalatlas.ai/funds/ra-capital-management) — Series B
- Rock Springs Capital — Series B
- UT Horizon Fund (https://capitalatlas.ai/funds/ut-horizon-fund) — Series B
- Ally Bridge Group (https://capitalatlas.ai/funds/ally-bridge-group) — Series B
- New Ground Ventures (https://capitalatlas.ai/funds/new-ground-ventures) — Series B
- Cowen Investment Management — Series B