# Septerna

Startup profile on Capital Atlas: https://capitalatlas.ai/startups/septerna

- Industry: Biotechnology
- Headquarters: San Francisco, US
- Website: www.septerna.com/
- Total disclosed funding: $174M
- Latest round: Series B (Jun 28, 2023)
- Investors on record: 15

## About

Based in California, US, and founded in 2019 by CEO Jeffrey Finer, Robert Lefkowitz, Arthur Christopoulos, and Patrick Sexton, Septerna, Inc. operates as a biotech company that develops an industrialized platform by combining the latest advances in biochemical, structural and computational drug discovery approaches to precisely control and modulate GPCR (G protein-coupled receptors) biology and pharmacology to discover and develop medicines. In July 2023, Septerna, Inc. raised USD 150 million in series B funding led by new investor RA Capital, with participation from other new investors Deep Track Capital, Driehaus Capital Management, Goldman Sachs Asset Management, Mirae Asset Financial Group, Soleus Capital Management, Vertex Ventures HC, and Woodline Partners. Returning investors BVF Partners, Casdin Capital, Catalio Capital Management, Invus, Logos Capital, Samsara BioCapital, Third Rock Ventures, and other unspecified investors also participated in the round. The company utilizes its proprietary native complex platform to recapitulate G protein-coupled receptors (GPCRs) with their dynamics, functions, and structures apart from the cellular environment to facilitate industrial-scale drug discovery for a wide range of diseases. Septerna’s pipeline includes GPCR medicines that target endocrine, CNS, and inflammation. The company plans to use its proceeds from January 2022 funding to advance its emerging pipeline of novel GPCR-targeted drug programs and span multiple therapeutic areas. In October 2024, Septerna, Inc. raised USD 288 million in an IPO, selling 16 million shares at USD 18 per share, above the expected USD 15-17 range, on the Nasdaq Global Select Market under the ticker symbol "SEPN." Septerna, Inc. has granted the underwriters a 30-day option to purchase up to an additional 2.4 million shares of common stock as part of the listing. Following the transaction, Third Rock Ventures retained a 20.8% minority stake and RA Capital retained a 6.7% minority stake in Septerna, Inc., respectively.

## Funding rounds

- Series B, Jun 28, 2023, $74M — Mirae Asset Global Investments, Third Rock Ventures, Goldman Sachs Asset Management, Driehaus Capital Management, Casdin Capital, Invus Financial Advisors, BVF Partners, RA Capital Management, Vertex Ventures HC, Samsara BioCapital, Soleus Capital, Woodline Partners, Logos Capital, Catalio Capital Management, Deep Track Capital
- Series A, Jan 27, 2022, $100M — Third Rock Ventures, Casdin Capital, Invus Financial Advisors, BVF Partners, Samsara BioCapital, Logos Capital, Catalio Capital Management

## Investors

- Third Rock Ventures (https://capitalatlas.ai/funds/third-rock-ventures) — Series A, Series B
- Casdin Capital (https://capitalatlas.ai/funds/casdin-capital) — Series A, Series B
- Invus Financial Advisors (https://capitalatlas.ai/funds/invus-financial-advisors) — Series A, Series B
- BVF Partners (https://capitalatlas.ai/funds/bvf-partners) — Series A, Series B
- Samsara BioCapital (https://capitalatlas.ai/funds/samsara-biocapital) — Series A, Series B
- Logos Capital (https://capitalatlas.ai/funds/logos-capital) — Series A, Series B
- Catalio Capital Management (https://capitalatlas.ai/funds/catalio-capital-management) — Series A, Series B
- Mirae Asset Global Investments (https://capitalatlas.ai/funds/mirae-asset-global-investments) — Series B
- Goldman Sachs Asset Management (https://capitalatlas.ai/funds/goldman-sachs-asset-management) — Series B
- Driehaus Capital Management (https://capitalatlas.ai/funds/driehaus-capital-management) — Series B
- RA Capital Management (https://capitalatlas.ai/funds/ra-capital-management) — Series B
- Vertex Ventures HC (https://capitalatlas.ai/funds/vertex-ventures-hc) — Series B
- Soleus Capital (https://capitalatlas.ai/funds/soleus-capital) — Series B
- Woodline Partners — Series B
- Deep Track Capital (https://capitalatlas.ai/funds/deep-track-capital) — Series B