# Profluent Bio

Startup profile on Capital Atlas: https://capitalatlas.ai/startups/profluent-bio

- Industry: Biotechnology
- Headquarters: Emeryville, US
- Website: www.profluent.bio
- Total disclosed funding: $115M
- Latest round: Series B (Nov 19, 2025)
- Investors on record: 8

## About

Founded in 2022 and based in California, US, Profluent Bio Inc. operates as a biotechnology company that develops novel functional proteins. The company was founded by its CEO, Ali Madani. In November 2025, Profluent Bio Inc. raised USD 106 million in series B funding co-led by new investors Altimeter Capital and Bezos Expeditions, with participation from returning investors Spark Capital, Insight Partners, AIX Ventures, Convergent Ventures and Air Street Capital.

Profluent Bio provides an artificial intelligence-based protein design research platform that leverages deep generative models, mainly machine learning models, to design and develop novel functional proteins, mainly biomolecules, for human health and industrial applications. The firm's AI-based biotechnology research platform decodes proteins with the help of deep generative models.

## Funding rounds

- Series B, Nov 19, 2025, $106M — Convergent Ventures, Insight Partners, Spark Capital, Altimeter Capital, Bezos Expeditions, Air Street Capital, AIX Ventures
- Seed, Jan 26, 2023, $9M — Convergent Ventures, Insight Partners, Phoenix Venture Partners, Air Street Capital, AIX Ventures

## Investors

- Convergent Ventures (https://capitalatlas.ai/funds/convergent-ventures) — Seed, Series B
- Insight Partners (https://capitalatlas.ai/funds/insight-partners) — Seed, Series B
- Phoenix Venture Partners — Seed
- Air Street Capital (https://capitalatlas.ai/funds/air-street-capital) — Seed, Series B
- AIX Ventures (https://capitalatlas.ai/funds/aix-ventures) — Seed, Series B
- Spark Capital — Series B
- Altimeter Capital (https://capitalatlas.ai/funds/altimeter-capital) — Series B
- Bezos Expeditions — Series B