# CRAIF

Startup profile on Capital Atlas: https://capitalatlas.ai/startups/craif

- Industry: Biotechnology
- Headquarters: Tokyo, Japan
- Website: www.craif.com
- Total disclosed funding: $68M
- Latest round: Series D (Aug 18, 2026)
- Investors on record: 23

## About

Established in 2018 and based in Tokyo, Japan, CRAIF Inc., formerly known as Icaria Inc., a healthcare technology and diagnostics firm that focuses on creating advanced disease detection technologies. The company specializes in non-invasive cancer screening through the analysis of urinary microRNA and its proprietary NANO IP technology. In August 2026, Craif Inc. raised JPY 4.8 billion in?series D funding co-led by Granite Asia and TAUNS Laboratories, Inc., with participation from Kodomonomori, Hokkaido Kyoso Partners, X&, Unreasonable Capital, Nagase Future Investments and a venture debt from  Joyo Bank, Higashi-Nippon Bank, North Pacific Bank, Hokkoku Bank, Nagoya Bank and Japan Finance Corporation. The round was part of a larger JPY 5.3 billion series D and debt funding.

Craif develops liquid biopsy tests utilizing exosomes, small particles released by cells. These tests analyze biomarkers found in urine to identify disease risks, particularly cancer. Craif's primary product, MySignal, is a cancer risk assessment test designed for early detection and prevention.

The company plans to use the August 2026 funding to expand U.S. research and development, product launch activities, scale MySignal cancer screening operations, support clinical development and regulatory approval of its pancreatic cancer SaMD program, and accelerate development of its urine-analysis platform for disease detection.

## Funding rounds

- Series D, Aug 18, 2026, $30M — Granite Asia, Unreasonable Capital, Hokkaido Kyoso Partners, X&, TAUNS Laboratories, Inc., Kodomonomori, Nagase Future Investments
- Series C, Jun 11, 2025 — Wing Capital Partners
- Series C, Apr 28, 2025, $12M — Unreasonable Capital, Aozora Corporate Investment, TAUNS Laboratories, Inc., Daiwa House Ventures, X&
- Series C, Dec 23, 2024, $6.4M — X&
- Series B, Apr 12, 2022, $2.6M — Kirin Holdings Company, Limited., Hakuhodo DY Ventures, Saisei Ventures, NOBUNAGA Capital Village
- Series B, Nov 2, 2021, $11M — Daiwa Corporate Investment, Tokio Marine & Nichido Fire Insurance Co., Aflac Corporate Ventures, MTG Ventures
- Series A, Jun 17, 2020, $6.1M — Daiwa Corporate Investment, Founders Fund, ANRI, Mori Trust, Aflac Corporate Ventures
- Seed, Feb 13, 2019 — ANRI, New Energy and Industrial Technology Development Organization, Japan Science and Technology Agency

## Investors

- ANRI (https://capitalatlas.ai/funds/anri) — Seed, Series A
- New Energy and Industrial Technology Development Organization — Seed
- Japan Science and Technology Agency — Seed
- Daiwa Corporate Investment (https://capitalatlas.ai/funds/daiwa-corporate-investment) — Series A, Series B
- Founders Fund (https://capitalatlas.ai/funds/founders-fund) — Series A
- Mori Trust — Series A
- Aflac Corporate Ventures (https://capitalatlas.ai/funds/aflac-corporate-ventures) — Series A, Series B
- Tokio Marine & Nichido Fire Insurance Co. — Series B
- MTG Ventures (https://capitalatlas.ai/funds/mtg-ventures) — Series B
- Kirin Holdings Company, Limited. — Series B
- Hakuhodo DY Ventures (https://capitalatlas.ai/funds/hakuhodo-dy-ventures) — Series B
- Saisei Ventures (https://capitalatlas.ai/funds/saisei-ventures) — Series B
- NOBUNAGA Capital Village (https://capitalatlas.ai/funds/nobunaga-capital-village) — Series B
- X& (https://capitalatlas.ai/funds/x) — Series C, Series D
- Unreasonable Capital (https://capitalatlas.ai/funds/unreasonable-capital) — Series C, Series D
- Aozora Corporate Investment (https://capitalatlas.ai/funds/aozora-corporate-investment) — Series C
- TAUNS Laboratories, Inc. — Series C, Series D
- Daiwa House Ventures (https://capitalatlas.ai/funds/daiwa-house-ventures) — Series C
- Wing Capital Partners (https://capitalatlas.ai/funds/wing-capital-partners) — Series C
- Granite Asia (https://capitalatlas.ai/funds/granite-asia) — Series D
- Hokkaido Kyoso Partners (https://capitalatlas.ai/funds/hokkaido-kyoso-partners) — Series D
- Kodomonomori — Series D
- Nagase Future Investments (https://capitalatlas.ai/funds/nagase-future-investments) — Series D